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Clinical Trial VICCPED0995

Title

Detection of Donor-Derived DNA in Semen Samples Among Recipients of Allogeneic Hematopoietic Stem-Cell Transplants

Principal Investigator(s)

Haydar Frangoul

Details

  • Protocol No. VICCPED0995
  • Open Date: 02/18/2010
  • Staging: N/A
  • Age Group: Both Child and Adult
  • Scope: Local
  • Objective: To examine semen samples from male survivors of allogeneic SCT for the presence of donor derived DNA
  • Disease Sites: Pediatrics; Leukemia
  • Therapies: Correlative
  • Drugs: None Specified
  • Participating Institutions: Vanderbilt University
  • National Clinical Trial ID: NCT01077440
  • Secondary Protocol No: Not Specified

Description

None Provided.

Eligibility

Ages Eligible for Study:18 Years and older
Genders Eligible for Study:Male
Accepts Healthy Volunteers:No

Criteria

DISEASE CHARACTERISTICS:
• Disease in remission
• More than 365 days since prior allogeneic hematopoietic stem cell transplantation with history of full donor engraftment
• Stable complete donor chimerism
PATIENT CHARACTERISTICS:
• Able to consent and willing to provide a semen sample
• Survivors who present for long-term follow-up appointments in the adult and pediatric stem cell transplant clinic at Vanderbilt University Medical Center
• No known history of infertility or azospermia
PRIOR CONCURRENT THERAPY:
• See Disease Characteristics
• No history of testicular irradiation ≥ 200 cGy