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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center

 

VICC toll-free number 1-877-936-8422

Melinda  Aldrich

Melinda Aldrich, Ph.D., M.P.H.

Assistant Professor of Thoracic Surgery

Contact Information:

609 Oxford House
1313 21st Ave. South
Nashville, TN 37232-4682
615-322-3386

Profile

Melinda Aldrich is an Assistant Professor in the Vanderbilt University School of Medicine. Her research focuses on identifying genetic and environmental factors contributing to health disparities in lung cancer incidence and survival. Dr. Aldrich's interests also include personalized genomic testing and pharmacogenetics.

Education
  • B.A., University of California, Santa Cruz, 1992
  • M.P.H., University of California, Berkeley, 2003 
  • Ph.D., University of California, Berkeley, 2007
 
Research Specialty

Genetic epidemiology, Racially diverse populations, Lung cancer, Pulmonary disease, Health disparities, Social and environmental factors, DNA databanks

Research Description

My research is focused on understanding why there are differences in lung cancer among different racial/ethnic populations. Specifically, my lab is focused on identifying genetic, social and environmental risk factors for lung cancer and its related phenotypes, such as nicotine addiction and pulmonary function. Investigating gene-environment and gene-gene interactions may explain some of the differences in disease between racial/ethnic groups.

Much of my research is centered on understanding how genetic differences in racial/ethnic background can influence risk of disease. African Americans have the highest lung cancer incidence and mortality compared to all other racial/ethnic groups. My lab is collaborating with Southern Community Cohort Study (SCCS) investigators and physician scientists to conduct comprehensive epidemiologic research to understand genetic and environmental factors influencing disease in racially mixed populations. We are currently identifying factors predicting lung cancer survival among low-income black and white adults participating in the SCCS. This research includes collecting genetic, clinical, biomarker and environmental data and then combining these data to understand lung cancer prognosis. Additional ongoing projects include identifying genetic factors influencing lung cancer risk in African Americans and using Vanderbilt’s electronic medical records linked to the DNA databank to investigate genetic factors contributing to improved cancer survival with metformin use. The contribution of genetic ancestry to complex disease and methods to use genetic ancestry to disentangle genetic and environmental risk factors is also being explored.

Publications
  • Grogan, EL, Deppen, SA, Ballman, KV, Andrade, GM, Verdial, FC, Aldrich, MC, Chen, CL, Decker, PA, Harpole, DH, Cerfolio, RJ, Keenan, RJ, Jones, DR, D''Amico, TA, Shrager, JB, Meyers, BF, Putnam, JB Accuracy of fluorodeoxyglucose-positron emission tomography within the clinical practice of the American College of Surgeons Oncology Group Z4031 trial to diagnose clinical stage I non-small cell lung cancer. Ann Thorac Surg, 97(4), 1142-8, 2014.
  • Deppen, SA, Grogan, EL, Aldrich, MC, Massion, PP Lung cancer screening and smoking cessation: a teachable moment. J Natl Cancer Inst, 106(6), 2014.
  • Aldrich, MC, Hidalgo, B, Widome, R, Briss, P, Brownson, RC, Teutsch, SM The role of epidemiology in evidence-based policy making: a case study of tobacco use in youth. Ann Epidemiol, 2014.
  • Monda, KL, Chen, GK, Taylor, KC, Palmer, C, Edwards, TL, Lange, LA, Ng, MC, Adeyemo, AA, Allison, MA, Bielak, LF, Chen, G, Graff, M, Irvin, MR, Rhie, SK, Li, G, Liu, Y, Liu, Y, Lu, Y, Nalls, MA, Sun, YV, Wojczynski, MK, Yanek, LR, Aldrich, MC, Ademola, A, Amos, CI, Bandera, EV, Bock, CH, Britton, A, Broeckel, U, Cai, Q, Caporaso, NE, Carlson, CS, Carpten, J, Casey, G, Chen, WM, Chen, F, Chen, YD, Chiang, CW, Coetzee, GA, Demerath, E, Deming-Halverson, SL, Driver, RW, Dubbert, P, Feitosa, MF, Feng, Y, Freedman, BI, Gillanders, EM, Gottesman, O, Guo, X, Haritunians, T, Harris, T, Harris, CC, Hennis, AJ, Hernandez, DG, McNeill, LH, Howard, TD, Howard, BV, Howard, VJ, Johnson, KC, Kang, SJ, Keating, BJ, Kolb, S, Kuller, LH, Kutlar, A, Langefeld, CD, Lettre, G, Lohman, K, Lotay, V, Lyon, H, Manson, JE, Maixner, W, Meng, YA, Monroe, KR, Morhason-Bello, I, Murphy, AB, Mychaleckyj, JC, Nadukuru, R, Nathanson, KL, Nayak, U, N''diaye, A, Nemesure, B, Wu, SY, Leske, MC, Neslund-Dudas, C, Neuhouser, M, Nyante, S, Ochs-Balcom, H, Ogunniyi, A, Ogundiran, TO, Ojengbede, O, Olopade, OI, Palmer, JR, Ruiz-Narvaez, EA, Palmer, ND, Press, MF, Rampersaud, E, Rasmussen-Torvik, LJ, Rodriguez-Gil, JL, Salako, B, Schadt, EE, Schwartz, AG, Shriner, DA, Siscovick, D, Smith, SB, Wassertheil-Smoller, S, Speliotes, EK, Spitz, MR, Sucheston, L, Taylor, H, Tayo, BO, Tucker, MA, Van Den Berg, DJ, Edwards, DR, Wang, Z, Wiencke, JK, Winkler, TW, Witte, JS, Wrensch, M, Wu, X, Yang, JJ, Levin, AM, Young, TR, Zakai, NA, Cushman, M, Zanetti, KA, Zhao, JH, Zhao, W, Zheng, Y, Zhou, J, Ziegler, RG, Zmuda, JM, Fernandes, JK, Gilkeson, GS, Kamen, DL, Hunt, KJ, Spruill, IJ, Ambrosone, CB, Ambs, S, Arnett, DK, Atwood, L, Becker, DM, Berndt, SI, Bernstein, L, Blot, WJ, Borecki, IB, Bottinger, EP, Bowden, DW, Burke, G, Chanock, SJ, Cooper, RS, Ding, J, Duggan, D, Evans, MK, Fox, C, Garvey, WT, Bradfield, JP, Hakonarson, H, Grant, SF, Hsing, A, Chu, L, Hu, JJ, Huo, D, Ingles, SA, John, EM, Jordan, JM, Kabagambe, EK, Kardia, SL, Kittles, RA, Goodman, PJ, Klein, EA, Kolonel, LN, Le Marchand, L, Liu, S, McKnight, B, Millikan, RC, Mosley, TH, Padhukasahasram, B, Williams, LK, Patel, SR, Peters, U, Pettaway, CA, Peyser, PA, Psaty, BM, Redline, S, Rotimi, CN, Rybicki, BA, Sale, MM, Schreiner, PJ, Signorello, LB, Singleton, AB, Stanford, JL, Strom, SS, Thun, MJ, Vitolins, M, Zheng, W, Moore, JH, Williams, SM, Ketkar, S, Zhu, X, Zonderman, AB, , , , , , , , , Kooperberg, C, Papanicolaou, GJ, Henderson, BE, Reiner, AP, Hirschhorn, JN, Loos, RJ, North, KE, Haiman, CA A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet, 45(6), 690-6, 2013.
  • Kodaman, N, Aldrich, MC, Smith, JR, Signorello, LB, Bradley, K, Breyer, J, Cohen, SS, Long, J, Cai, Q, Giles, J, Bush, WS, Blot, WJ, Matthews, CE, Williams, SM A small number of candidate gene SNPs reveal continental ancestry in African Americans. Ann Hum Genet, 77(1), 56-66, 2013.
  • Hiatt, RA, Sulsky, S, Aldrich, MC, Kreiger, N, Rothenberg, R Promoting innovation and creativity in epidemiology for the 21st century. Ann Epidemiol, 23(7), 452-4, 2013.
  • Aldrich, MC, Selvin, S, Wrensch, MR, Sison, JD, Hansen, HM, Quesenberry, CP, Seldin, MF, Barcellos, LF, Buffler, PA, Wiencke, JK Socioeconomic status and lung cancer: unraveling the contribution of genetic admixture. Am J Public Health, 103(10), e73-80, 2013.
  • Aldrich, MC, Grogan, EL, Munro, HM, Signorello, LB, Blot, WJ Stage-adjusted lung cancer survival does not differ between low-income Blacks and Whites. J Thorac Oncol, 8(10), 1248-54, 2013.
  • Metayer, C, Zhang, L, Wiemels, JL, Bartley, K, Schiffman, J, Ma, X, Aldrich, MC, Chang, JS, Selvin, S, Fu, CH, Ducore, J, Smith, MT, Buffler, PA Tobacco smoke exposure and the risk of childhood acute lymphoblastic and myeloid leukemias by cytogenetic subtype. Cancer Epidemiol Biomarkers Prev, 22(9), 1600-11, 2013.
  • Liu, M, Shah, A, Jiang, M, Peterson, NB, Dai, Q, Aldrich, MC, Chen, Q, Bowton, EA, Liu, H, Denny, JC, Xu, H A study of transportability of an existing smoking status detection module across institutions. AMIA Annu Symp Proc, 2012577-86, 2012.
  • Deppen, SA, Aldrich, MC, Hartge, P, Berg, CD, Colditz, GA, Petitti, DB, Hiatt, RA Cancer screening: the journey from epidemiology to policy. Ann Epidemiol, 22(6), 439-45, 2012.
  • Jacobs, KB, Yeager, M, Zhou, W, Wacholder, S, Wang, Z, Rodriguez-Santiago, B, Hutchinson, A, Deng, X, Liu, C, Horner, MJ, Cullen, M, Epstein, CG, Burdett, L, Dean, MC, Chatterjee, N, Sampson, J, Chung, CC, Kovaks, J, Gapstur, SM, Stevens, VL, Teras, LT, Gaudet, MM, Albanes, D, Weinstein, SJ, Virtamo, J, Taylor, PR, Freedman, ND, Abnet, CC, Goldstein, AM, Hu, N, Yu, K, Yuan, JM, Liao, L, Ding, T, Qiao, YL, Gao, YT, Koh, WP, Xiang, YB, Tang, ZZ, Fan, JH, Aldrich, MC, Amos, C, Blot, WJ, Bock, CH, Gillanders, EM, Harris, CC, Haiman, CA, Henderson, BE, Kolonel, LN, Le Marchand, L, McNeill, LH, Rybicki, BA, Schwartz, AG, Signorello, LB, Spitz, MR, Wiencke, JK, Wrensch, M, Wu, X, Zanetti, KA, Ziegler, RG, Figueroa, JD, Garcia-Closas, M, Malats, N, Marenne, G, Prokunina-Olsson, L, Baris, D, Schwenn, M, Johnson, A, Landi, MT, Goldin, L, Consonni, D, Bertazzi, PA, Rotunno, M, Rajaraman, P, Andersson, U, Beane Freeman, LE, Berg, CD, Buring, JE, Butler, MA, Carreon, T, Feychting, M, Ahlbom, A, Gaziano, JM, Giles, GG, Hallmans, G, Hankinson, SE, Hartge, P, Henriksson, R, Inskip, PD, Johansen, C, Landgren, A, McKean-Cowdin, R, Michaud, DS, Melin, BS, Peters, U, Ruder, AM, Sesso, HD, Severi, G, Shu, XO, Visvanathan, K, White, E, Wolk, A, Zeleniuch-Jacquotte, A, Zheng, W, Silverman, DT, Kogevinas, M, Gonzalez, JR, Villa, O, Li, D, Duell, EJ, Risch, HA, Olson, SH, Kooperberg, C, Wolpin, BM, Jiao, L, Hassan, M, Wheeler, W, Arslan, AA, Bueno-de-Mesquita, HB, Fuchs, CS, Gallinger, S, Gross, MD, Holly, EA, Klein, AP, LaCroix, A, Mandelson, MT, Petersen, G, Boutron-Ruault, MC, Bracci, PM, Canzian, F, Chang, K, Cotterchio, M, Giovannucci, EL, Goggins, M, Hoffman Bolton, JA, Jenab, M, Khaw, KT, Krogh, V, Kurtz, RC, McWilliams, RR, Mendelsohn, JB, Rabe, KG, Riboli, E, Tj¿¿nneland, A, Tobias, GS, Trichopoulos, D, Elena, JW, Yu, H, Amundadottir, L, Stolzenberg-Solomon, RZ, Kraft, P, Schumacher, F, Stram, D, Savage, SA, Mirabello, L, Andrulis, IL, Wunder, JS, Pati¿¿o Garc¿¿a, A, Sierrases¿¿maga, L, Barkauskas, DA, Gorlick, RG, Purdue, M, Chow, WH, Moore, LE, Schwartz, KL, Davis, FG, Hsing, AW, Berndt, SI, Black, A, Wentzensen, N, Brinton, LA, Lissowska, J, Peplonska, B, McGlynn, KA, Cook, MB, Graubard, BI, Kratz, CP, Greene, MH, Erickson, RL, Hunter, DJ, Thomas, G, Hoover, RN, Real, FX, Fraumeni, JF, Caporaso, NE, Tucker, M, Rothman, N, P¿¿rez-Jurado, LA, Chanock, SJ Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet, 44(6), 651-8, 2012.
  • Aldrich, MC, Kumar, R, Colangelo, LA, Williams, LK, Sen, S, Kritchevsky, SB, Meibohm, B, Galanter, J, Hu, D, Gignoux, CR, Liu, Y, Harris, TB, Ziv, E, Zmuda, J, Garcia, M, Leak, TS, Foreman, MG, Smith, LJ, Fornage, M, Liu, K, Burchard, EG, , Genetic ancestry-smoking interactions and lung function in African Americans: a cohort study. PLoS One, 7(6), e39541, 2012.
  • Wilk, JB, Shrine, NR, Loehr, LR, Zhao, JH, Manichaikul, A, Lopez, LM, Smith, AV, Heckbert, SR, Smolonska, J, Tang, W, Loth, DW, Curjuric, I, Hui, J, Cho, MH, Latourelle, JC, Henry, AP, Aldrich, M, Bakke, P, Beaty, TH, Bentley, AR, Borecki, IB, Brusselle, GG, Burkart, KM, Chen, TH, Couper, D, Crapo, JD, Davies, G, Dupuis, J, Franceschini, N, Gulsvik, A, Hancock, DB, Harris, TB, Hofman, A, Imboden, M, James, AL, Khaw, KT, Lahousse, L, Launer, LJ, Litonjua, A, Liu, Y, Lohman, KK, Lomas, DA, Lumley, T, Marciante, KD, McArdle, WL, Meibohm, B, Morrison, AC, Musk, AW, Myers, RH, North, KE, Postma, DS, Psaty, BM, Rich, SS, Rivadeneira, F, Rochat, T, Rotter, JI, Soler Artigas, M, Starr, JM, Uitterlinden, AG, Wareham, NJ, Wijmenga, C, Zanen, P, Province, MA, Silverman, EK, Deary, IJ, Palmer, LJ, Cassano, PA, Gudnason, V, Barr, RG, Loos, RJ, Strachan, DP, London, SJ, Boezen, HM, Probst-Hensch, N, Gharib, SA, Hall, IP, O''Connor, GT, Tobin, MD, Stricker, BH Genome Wide Association Studies Identify CHRNA5/3 and HTR4 in the Development of Airflow Obstruction. Am J Respir Crit Care Med, 2012.
  • Hancock, DB, Artigas, MS, Gharib, SA, Henry, A, Manichaikul, A, Ramasamy, A, Loth, DW, Imboden, M, Koch, B, McArdle, WL, Smith, AV, Smolonska, J, Sood, A, Tang, W, Wilk, JB, Zhai, G, Zhao, JH, Aschard, H, Burkart, KM, Curjuric, I, Eijgelsheim, M, Elliott, P, Gu, X, Harris, TB, Janson, C, Homuth, G, Hysi, PG, Liu, JZ, Loehr, LR, Lohman, K, Loos, RJ, Manning, AK, Marciante, KD, Obeidat, M, Postma, DS, Aldrich, MC, Brusselle, GG, Chen, TH, Eiriksdottir, G, Franceschini, N, Heinrich, J, Rotter, JI, Wijmenga, C, Williams, OD, Bentley, AR, Hofman, A, Laurie, CC, Lumley, T, Morrison, AC, Joubert, BR, Rivadeneira, F, Couper, DJ, Kritchevsky, SB, Liu, Y, Wjst, M, Wain, LV, Vonk, JM, Uitterlinden, AG, Rochat, T, Rich, SS, Psaty, BM, O''Connor, GT, North, KE, Mirel, DB, Meibohm, B, Launer, LJ, Khaw, KT, Hartikainen, AL, Hammond, CJ, Gl¿¿ser, S, Marchini, J, Kraft, P, Wareham, NJ, V¿¿lzke, H, Stricker, BH, Spector, TD, Probst-Hensch, NM, Jarvis, D, Jarvelin, MR, Heckbert, SR, Gudnason, V, Boezen, HM, Barr, RG, Cassano, PA, Strachan, DP, Fornage, M, Hall, IP, Dupuis, J, Tobin, MD, London, SJ Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. PLoS Genet, 8(12), e1003098, 2012.
  • St Julien, JB, Aldrich, MC, Sheng, S, Deppen, SA, Burfeind, WR, Putnam, JB, Lambright, ES, Nesbitt, JC, Grogan, EL Obesity increases operating room time for lobectomy in the society of thoracic surgeons database. Ann Thorac Surg, 94(6), 1841-7, 2012.
  • St Julien, JB, Pinkerman, R, Aldrich, MC, Chen, H, Deppen, SA, Callaway-Lane, C, Massion, P, Putnam, JB, Lambright, ES, Nesbitt, JC, Grogan, EL Poor survival for veterans with pathologic stage I non-small-cell lung cancer. Am J Surg, 2012.
  • Slusky, DA, Metayer, C, Aldrich, MC, Ward, MH, Lea, CS, Selvin, S, Buffler, PA Reliability of maternal-reports regarding the use of household pesticides: Experience from a case-control study of childhood leukemia. Cancer Epidemiol, 36(4), 375-80, 2012.
  • Hassanein, M, Callison, JC, Callaway-Lane, C, Aldrich, MC, Grogan, EL, Massion, PP The state of molecular biomarkers for the early detection of lung cancer. Cancer Prev Res (Phila), 5(8), 992-1006, 2012.
  • Chokkalingam, AP, Metayer, C, Scelo, GA, Chang, JS, Urayama, KY, Aldrich, MC, Guha, N, Hansen, HM, Dahl, GV, Barcellos, LF, Wiencke, JK, Wiemels, JL, Buffler, PA Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemia. Cancer Causes Control, 23(8), 1367-75, 2012.
  • Galanter, JM, Torgerson, D, Gignoux, CR, Sen, S, Roth, LA, Via, M, Aldrich, MC, Eng, C, Huntsman, S, Rodriguez-Santana, J, Rodriguez-Cintron, W, Chapela, R, Ford, JG, Burchard, EG Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations. J Allergy Clin Immunol, 128(1), 37-43.e12, 2011.
  • Metayer, C, Scelo, G, Chokkalingam, AP, Barcellos, LF, Aldrich, MC, Chang, JS, Guha, N, Urayama, KY, Hansen, HM, Block, G, Kiley, V, Wiencke, JK, Wiemels, JL, Buffler, PA Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia. Cancer Causes Control, 22(9), 1243-58, 2011.
  • Soler Artigas, M, Loth, DW, Wain, LV, Gharib, SA, Obeidat, M, Tang, W, Zhai, G, Zhao, JH, Smith, AV, Huffman, JE, Albrecht, E, Jackson, CM, Evans, DM, Cadby, G, Fornage, M, Manichaikul, A, Lopez, LM, Johnson, T, Aldrich, MC, Aspelund, T, Barroso, I, Campbell, H, Cassano, PA, Couper, DJ, Eiriksdottir, G, Franceschini, N, Garcia, M, Gieger, C, Gislason, GK, Grkovic, I, Hammond, CJ, Hancock, DB, Harris, TB, Ramasamy, A, Heckbert, SR, Heli¿¿vaara, M, Homuth, G, Hysi, PG, James, AL, Jankovic, S, Joubert, BR, Karrasch, S, Klopp, N, Koch, B, Kritchevsky, SB, Launer, LJ, Liu, Y, Loehr, LR, Lohman, K, Loos, RJ, Lumley, T, Al Balushi, KA, Ang, WQ, Barr, RG, Beilby, J, Blakey, JD, Boban, M, Boraska, V, Brisman, J, Britton, JR, Brusselle, GG, Cooper, C, Curjuric, I, Dahgam, S, Deary, IJ, Ebrahim, S, Eijgelsheim, M, Francks, C, Gaysina, D, Granell, R, Gu, X, Hankinson, JL, Hardy, R, Harris, SE, Henderson, J, Henry, A, Hingorani, AD, Hofman, A, Holt, PG, Hui, J, Hunter, ML, Imboden, M, Jameson, KA, Kerr, SM, Kolcic, I, Kronenberg, F, Liu, JZ, Marchini, J, McKeever, T, Morris, AD, Olin, AC, Porteous, DJ, Postma, DS, Rich, SS, Ring, SM, Rivadeneira, F, Rochat, T, Sayer, AA, Sayers, I, Sly, PD, Smith, GD, Sood, A, Starr, JM, Uitterlinden, AG, Vonk, JM, Wannamethee, SG, Whincup, PH, Wijmenga, C, Williams, OD, Wong, A, Mangino, M, Marciante, KD, McArdle, WL, Meibohm, B, Morrison, AC, North, KE, Omenaas, E, Palmer, LJ, Pietil¿¿inen, KH, Pin, I, Pola Sbreve Ek, O, Pouta, A, Psaty, BM, Hartikainen, AL, Rantanen, T, Ripatti, S, Rotter, JI, Rudan, I, Rudnicka, AR, Schulz, H, Shin, SY, Spector, TD, Surakka, I, Vitart, V, V¿¿lzke, H, Wareham, NJ, Warrington, NM, Wichmann, HE, Wild, SH, Wilk, JB, Wjst, M, Wright, AF, Zgaga, L, Zemunik, T, Pennell, CE, Nyberg, F, Kuh, D, Holloway, JW, Boezen, HM, Lawlor, DA, Morris, RW, Probst-Hensch, N, , , , , Kaprio, J, Wilson, JF, Hayward, C, K¿¿h¿¿nen, M, Heinrich, J, Musk, AW, Jarvis, DL, Gl¿¿ser, S, J¿¿rvelin, MR, Ch Stricker, BH, Elliott, P, O''Connor, GT, Strachan, DP, London, SJ, Hall, IP, Gudnason, V, Tobin, MD Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet, 43(11), 1082-90, 2011.
  • Chokkalingam, AP, Bartley, K, Wiemels, JL, Metayer, C, Barcellos, LF, Hansen, HM, Aldrich, MC, Guha, N, Urayama, KY, Scelo, G, Chang, JS, Month, SR, Wiencke, JK, Buffler, PA Haplotypes of DNA repair and cell cycle control genes, X-ray exposure, and risk of childhood acute lymphoblastic leukemia. Cancer Causes Control, 22(12), 1721-30, 2011.
  • Blot, WJ, Cohen, SS, Aldrich, M, McLaughlin, JK, Hargreaves, MK, Signorello, LB Lung cancer risk among smokers of menthol cigarettes. J Natl Cancer Inst, 103(10), 810-6, 2011.
  • Chokkalingam, AP, Aldrich, MC, Bartley, K, Hsu, LI, Metayer, C, Barcellos, LF, Wiemels, JL, Wiencke, JK, Buffler, PA, Selvin, S Matching on Race and Ethnicity in Case-Control Studies as a Means of Control for Population Stratification. Epidemiology (Sunnyvale), 1101, 2011.
  • Hinch, AG, Tandon, A, Patterson, N, Song, Y, Rohland, N, Palmer, CD, Chen, GK, Wang, K, Buxbaum, SG, Akylbekova, EL, Aldrich, MC, Ambrosone, CB, Amos, C, Bandera, EV, Berndt, SI, Bernstein, L, Blot, WJ, Bock, CH, Boerwinkle, E, Cai, Q, Caporaso, N, Casey, G, Cupples, LA, Deming, SL, Diver, WR, Divers, J, Fornage, M, Gillanders, EM, Glessner, J, Harris, CC, Hu, JJ, Ingles, SA, Isaacs, W, John, EM, Kao, WH, Keating, B, Kittles, RA, Kolonel, LN, Larkin, E, Le Marchand, L, McNeill, LH, Millikan, RC, Murphy, A, Musani, S, Neslund-Dudas, C, Nyante, S, Papanicolaou, GJ, Press, MF, Psaty, BM, Reiner, AP, Rich, SS, Rodriguez-Gil, JL, Rotter, JI, Rybicki, BA, Schwartz, AG, Signorello, LB, Spitz, M, Strom, SS, Thun, MJ, Tucker, MA, Wang, Z, Wiencke, JK, Witte, JS, Wrensch, M, Wu, X, Yamamura, Y, Zanetti, KA, Zheng, W, Ziegler, RG, Zhu, X, Redline, S, Hirschhorn, JN, Henderson, BE, Taylor, HA, Price, AL, Hakonarson, H, Chanock, SJ, Haiman, CA, Wilson, JG, Reich, D, Myers, SR The landscape of recombination in African Americans. Nature, 476(7359), 170-5, 2011.
  • Kumar, R, Seibold, MA, Aldrich, MC, Williams, LK, Reiner, AP, Colangelo, L, Galanter, J, Gignoux, C, Hu, D, Sen, S, Choudhry, S, Peterson, EL, Rodriguez-Santana, J, Rodriguez-Cintron, W, Nalls, MA, Leak, TS, O''Meara, E, Meibohm, B, Kritchevsky, SB, Li, R, Harris, TB, Nickerson, DA, Fornage, M, Enright, P, Ziv, E, Smith, LJ, Liu, K, Burchard, EG Genetic ancestry in lung-function predictions. N Engl J Med, 363(4), 321-30, 2010.
  • Chang, JS, Wiemels, JL, Chokkalingam, AP, Metayer, C, Barcellos, LF, Hansen, HM, Aldrich, MC, Guha, N, Urayama, KY, Scelo, G, Green, J, May, SL, Kiley, VA, Wiencke, JK, Buffler, PA Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev, 19(9), 2152-63, 2010.
  • Chang, JS, Wrensch, MR, Hansen, HM, Sison, JD, Aldrich, MC, Quesenberry, CP, Seldin, MF, Kelsey, KT, Wiencke, JK Base excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African-Americans. Carcinogenesis, 30(1), 78-87, 2009.
  • Aldrich, MC, Selvin, S, Hansen, HM, Barcellos, LF, Wrensch, MR, Sison, JD, Kelsey, KT, Buffler, PA, Quesenberry, CP, Seldin, MF, Wiencke, JK CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification. Cancer Res, 69(6), 2340-8, 2009.
  • Scelo, G, Metayer, C, Zhang, L, Wiemels, JL, Aldrich, MC, Selvin, S, Month, S, Smith, MT, Buffler, PA Household exposure to paint and petroleum solvents, chromosomal translocations, and the risk of childhood leukemia. Environ Health Perspect, 117(1), 133-9, 2009.
  • Aldrich, MC, Selvin, S, Hansen, HM, Barcellos, LF, Wrensch, MR, Sison, JD, Quesenberry, CP, Kittles, RA, Silva, G, Buffler, PA, Seldin, MF, Wiencke, JK Comparison of statistical methods for estimating genetic admixture in a lung cancer study of African Americans and Latinos. Am J Epidemiol, 168(9), 1035-46, 2008.
  • Chang, JS, Wrensch, MR, Hansen, HM, Sison, JD, Aldrich, MC, Quesenberry, CP, Seldin, MF, Kelsey, KT, Kittles, RA, Silva, G, Wiencke, JK Nucleotide excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African Americans. Int J Cancer, 123(9), 2095-104, 2008.
  • Aldrich, MC, Zhang, L, Wiemels, JL, Ma, X, Loh, ML, Metayer, C, Selvin, S, Feusner, J, Smith, MT, Buffler, PA Cytogenetics of Hispanic and White children with acute lymphoblastic leukemia in California. Cancer Epidemiol Biomarkers Prev, 15(3), 578-81, 2006.
  • Reader, JR, Hyde, DM, Schelegle, ES, Aldrich, MC, Stoddard, AM, McLane, MP, Levitt, RC, Tepper, JS Interleukin-9 induces mucous cell metaplasia independent of inflammation. Am J Respir Cell Mol Biol, 28(6), 664-72, 2003.
  • Reader, JR, Tepper, JS, Schelegle, ES, Aldrich, MC, Putney, LF, Pfeiffer, JW, Hyde, DM Pathogenesis of mucous cell metaplasia in a murine asthma model. Am J Pathol, 162(6), 2069-78, 2003.
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