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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center

 

Thomas M. Aune, Ph.D.

Professor of Medicine (Rheumatology)
Associate Professor of Pathology, Microbiology and Immunology
Researcher

Contact Information:

Vanderbilt University Medical Center
T-3219 Medical Center North
Nashville, TN 37232
615-343-7353

Research Specialty

Our research focuses on the use of functional genomic and epigenetic approaches to understand gene regulation.

Research Description

Our research focuses on the use of functional genomic and epigenetic approaches to understand gene regulation. Our interests range from detailed mechanistic studies of the interferon-gamma gene, a key cytokine produced by cells of the innate and adaptive immune system, a critical cytokine required to induce cell-mediated inflammation to the use of these approaches to gain new insights into human disease, including diseases of the endocrine system. These include recent studies evaluating relationships among gene expression signatures in atherosclerosis, type 2 diabetes and metabolic syndrome and study of copy number polymorphisms in type 1 diabetes, type 2 diabetes, and multiple sclerosis.

Publications