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Vanderbilt-Ingram Cancer CenterVanderbilt-Ingram Cancer Center


VICC toll-free number 1-877-936-8422

Funding Opportunities

Deadline: Monday, April 30, 2012 by 5 p.m.

NCI launched the "Provocative Questions" initiative to engage the cancer research community in addressing important problems and paradoxes in cancer research. The list of 24 novel questions will guide the NCI in efforts to control cancer through laboratory, clinical and population sciences. RFAs for R21 and R01 applications were released last fall and applications are currently under review.

Vanderbilt-Ingram is pleased to announce the availability of funds to generate preliminary data to respond to a future NCI Provocative Question RFA. These funds will support projects that challenge cancer researchers to think about specific problems in key areas of cancer research that are deemed important but have not received sufficient attention. The areas of focus fall into 3 broad categories:

  • Ignored or neglected cancer-related problems for which satisfactory, rigorous research answers are still lacking
  • Recent findings that are perplexing or paradoxical, revealing important gaps in current knowledge
  • Problems perceived as particularly difficult to explore but may now be addressed as a result of recent scientific discoveries and technical advances

Funds are available to all VICC members and will support projects from individual investigators or collaborative teams. Original cancer-related projects with the potential to develop into independent R21 or R01 grants are encouraged. We anticipate awarding 3 grants with individual awards limited to a maximum of $75,000 (direct costs). All grants will be evaluated by peer review and will be funded for a 1-year period beginning July 1, 2012.

Applications will include the following (in NIH format):

  1. One-page title, specific aims and statement that identifies one (and only one) specific Provocative Question addressed in the proposed project and a brief description of how the research will uniquely provide an answer to the question
  2. Two-page research strategy section to include background, rationale, research design and methods and preliminary data (if available)
  3. One-year budget and budget justification
  4. Two-page NIH biosketch for each key investigator

The deadline for applications is Monday, April 30, 2012 by 5 p.m.
Deadline extended to May 7, 2012 by 5 p.m.

Please email your applications (PDF format) to Brandon Fox.

The awards will be announced in June 2012.

List of 24 Provocative Questions (PDF)

For more information, you can contact Brandon Fox or visit the NCI website. In addition to listing the 24 questions, this website gives some background on the following:

  • Importance of each question
  • A discussion of the feasibility of research on the specific question
  • Commentary on the implications of successfully being able to address the question