Phase III Randomized Trial of Standard Systemic Therapy (SST) versus Standard Systemic Therapy Plus Definitive Treatment (Surgery or Radiation) of the Primary Tumor in Metastatic Prostate Cancer
Prostate
Prostate
Prostate
III
Schaffer, Kerry
NCT03678025
SWOGUROS1802
A Phase 3, Randomized, Open-Label, Study to Compare the Efficacy and Safety of Adjuvant MK-2870 in Combination with Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice (TPC) in Participants with Triple-Negative Breast Cancer (TNBC) Who Received Neoadjuvant Therapy and Did Not Achieve a Pathological Complete Response (pCR) at Surgery
Breast
Breast
Breast
III
Kennedy, Laura
NCT06393374
VICC-DTBRE23439
A Phase II Study of Ipilimumab, Cabozantinib, and Nivolumab in Rare Genitourinary Cancers (ICONIC)
Multiple Cancer Types
Bladder,
Kidney (Renal Cell),
Rectal
II
Schaffer, Kerry
NCT03866382
ALLIANCEUROA031702
A Phase I/IIa, Open-label, Multi-center Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the ATR Kinase Inhibitor ART0380 Administered Orally as Monotherapy and in Combination to Patients with Advanced or Metastatic Solid Tumors
Miscellaneous
Miscellaneous
Miscellaneous
I/II
Cardin, Dana
NCT04657068
VICCGIP25035
A Phase 1, Open-Label, Multicenter Study of INCB160058 in Participants with Myeloproliferative Neoplasms
Not Available
I
Kishtagari, Ashwin
NCT06313593
VICC-DTHEM24055P
A Phase 1, Open-Label, Multicenter Study of INCA033989 Administered as a Monotherapy or in Combination with Ruxolitinib in Participants with Myeloproliferative Neoplasms
Leukemia
Leukemia
Leukemia
I
Mohan, Sanjay
NCT06034002
VICC-DTHEM23416P
Multicenter, Open-Label, Phase 3 Study of Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Subjects with Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease after Failure of Rituximab or Rituximab and Chemotherapy (ALLELE Study)
Hematologic
Hematologic
Hematologic
III
Dholaria, Bhagirathbhai
NCT03394365
VICCCTT1875
A Phase 3 Randomized, Double-Blind, Active-Controlled Study of Palazestrant with Ribociclib Versus Letrozole with Ribociclib for the First-Line Treatment of ER+, HER2- Advanced Breast Cancer (OPERA-02)
Breast
Breast
Breast
III
Abramson, Vandana
NCT07085767
VICCBRE25043
A Phase 2 Dose Optimization Trial Evaluating a CD46-Targeted Antibody-Drug Conjugate (FG-3246) in Patients with Metastatic Castration-Resistant Prostate Cancer
Prostate
Prostate
Prostate
II
Schaffer, Kerry
NCT06842498
VICCURO24538
NRG-CC015: Harnessing E-Mindfulness Approaches for Living-After Breast Cancer---HEAL-ABC
Breast
Breast
Breast
III
Kennedy, Laura
NCT06748222
NRGBRECC015