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BBO-11818 in Adult Subjects With KRAS Mutant Cancer

Multiple Cancer Types

A first in human study to evaluate the safety and preliminary antitumor activity of BBO-11818, a pan-KRAS inhibitor, in subjects with locally advanced unresectable or metastatic KRAS mutant solid tumors.
Colon, Lung, Miscellaneous, Pancreatic
I
Eng, Cathy
NCT06917079
VICCPHI25051

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Multiple Cancer Types

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon cancer.
Colon, Rectal
II/III
Ciombor, Kristen
NCT05174169
SWOGGI008