Clinical Trials Search at Vanderbilt-Ingram Cancer Center
Near Infrared Autofluorescence via PTeye for the Detection of Parathyroid Glands during Total Thyroid Surgery
This trial studies how well infrared autofluorescence via PTeye works in detecting parathyroid glands during total thyroid surgery. Located closely to the thyroid gland are the parathyroid glands, which are important organs that regulate calcium levels in the body. Thus, it is essential for a surgeon to correctly identify this structure when performing a thyroid surgery. PTeye may help surgeon to identify and preserve healthy parathyroid glands during surgery. By assisting the surgeon in correctly identifying parathyroid glands, this device may improve the quality of the operation performed on the patient.
Fluid Measurements and MRI in Determining Biomarkers of Lymphatic Dysfunction in Patients with Breast Cancer
This trial uses fluid measurements of the arm and MRI to determine biomarkers of lymphatic dysfunction in patients with breast cancer. Studying the lymphatic system (the part of your body that helps to process and clear waste products) in different ways will help doctors understand more about lymphedema (excess fluid after lymph nodes are removed) and help with prevention and management of lymphedema in patients with breast cancer.
Testing Whether A Novel MRI Imaging Approach Will Find Aggressive Disease before Surgery, which May Help Physicians Decide the Best Treatment Plan for Patients with Newly Diagnosed Prostate Cancer
This phase II trial studies how well multiparametric magnetic resonance imaging (MRI) works in evaluating cancer stage and helping treatment planning in patients with prostate cancer. Multiparametric MRI may be useful for evaluating the type of cancer in finding aggressive disease.
Genetic Testing in Screening Patients with Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)
Multiple Cancer Types
This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient’s tumor cells may help doctors select the best treatment for patients that have certain genetic changes.
Lung, Non Small Cell
This trial investigates how well near infrared autofluorescence imaging works in identifying parathyroid glands during surgery to remove one or more parathyroid glands (parathyroidectomy). The parathyroid gland is an important organ in the neck that regulates calcium levels in the body. Thus, it is essential for a surgeon to correctly identify this organ when performing parathyroid surgeries. By assisting the surgeon in correctly identifying a diseased parathyroid gland, the 'PTeye' near infrared autofluorescence imaging device may improve the quality of the operation performed on the patient. This trial may determine if the ‘PTeye’ truly benefits a patient undergoing surgery for parathyroid disease or not.
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients with Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
Multiple Cancer Types
This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and / or for which no standard treatment exists that has been shown to prolong survival. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with genetic changes or abnormalities (mutations) may benefit more from treatment which targets their tumor's particular genetic mutation, and may help doctors plan better treatment for patients with solid tumors or non-Hodgkin lymphomas.
Lymphoma, Miscellaneous, Pediatric Solid Tumors
This randomized phase III trial studies digital tomosynthesis mammography and digital mammography in screening patients for breast cancer. Screening for breast cancer with tomosynthesis mammography may be superior to digital mammography for breast cancer screening and may help reduce the need for additional imaging or treatment.
Multiple Cancer Types
Lung, Non Small Cell, Small Cell