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BBO-11818 in Adult Subjects With KRAS Mutant Cancer

Multiple Cancer Types

A first in human study to evaluate the safety and preliminary antitumor activity of BBO-11818, a pan-KRAS inhibitor, in subjects with locally advanced unresectable or metastatic KRAS mutant solid tumors.
Colon, Lung, Miscellaneous, Pancreatic
I
Eng, Cathy
NCT06917079
VICCPHI25051

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

Miscellaneous

Phase 1 dose escalation and expansion study of CLSP-1025, a first-in-class HLA-A\*02:01 specific T cell engager (TCE) targeting solid tumors that harbor the p53 R175H mutation.
Miscellaneous
I
Berlin, Jordan
NCT06778863
VICCPHI24572