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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

Multiple Cancer Types

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon cancer.
Colon, Rectal
II/III
Ciombor, Kristen
NCT05174169
SWOGGI008

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

Multiple Cancer Types

The main purpose of this study is to assess safety \& tolerability and antitumor activity of LY3962673 as monotherapy and in combination with other chemotherapy agents in participants with KRAS G12D-mutant advanced solid tumor types. The study is expected to last approximately 5 years.
Colon, Esophageal, Gastric/Gastroesophageal, Gastrointestinal, Lung, Non Small Cell, Pancreatic, Phase I, Rectal, Uterine
I
Cardin, Dana
NCT06586515
VICC-DTGIT24002P