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Clinical Trials Search at Vanderbilt-Ingram Cancer Center



A Disease Registry of Patients With Mantle Cell Lymphoma

Lymphoma

The purpose of this study is to create a patient registry in order to assess treatment patterns, physician reported clinical outcomes and patient-reported health-related quality of life among patients diagnosed with Mantle Cell Lymphoma (MCL) who newly initiated a novel therapy in the past 3 months and treatment is ongoing at the time of enrollment.
Lymphoma
N/A
Reddy, Nishitha
NCT03816683
VICCPCL18150

Aspirin in Preventing Colorectal Cancer in Patients with Colorectal Adenoma

Multiple Cancer Types

This phase IIa trial studies how well aspirin works in preventing colorectal cancer in patients with colorectal adenoma. Aspirin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Colon, Rectal
II
Dai, Qi
NCT02965703
VICCGI17105

Near Infrared Autofluorescence Imaging for Identifying Parathyroid Glands during Parathyroidectomy

Endocrine

This trial investigates how well near infrared autofluorescence imaging works in identifying parathyroid glands during surgery to remove one or more parathyroid glands (parathyroidectomy). The parathyroid gland is an important organ in the neck that regulates calcium levels in the body. Thus, it is essential for a surgeon to correctly identify this organ when performing parathyroid surgeries. By assisting the surgeon in correctly identifying a diseased parathyroid gland, the 'PTeye' near infrared autofluorescence imaging device may improve the quality of the operation performed on the patient. This trial may determine if the ‘PTeye’ truly benefits a patient undergoing surgery for parathyroid disease or not.
Endocrine
N/A
Solorzano, Carmen
NCT04299425
VICCHN2063

Near Infrared Autofluorescence via PTeye for the Detection of Parathyroid Glands during Total Thyroid Surgery

Thyroid

This trial studies how well infrared autofluorescence via PTeye works in detecting parathyroid glands during total thyroid surgery. Located closely to the thyroid gland are the parathyroid glands, which are important organs that regulate calcium levels in the body. Thus, it is essential for a surgeon to correctly identify this structure when performing a thyroid surgery. PTeye may help surgeon to identify and preserve healthy parathyroid glands during surgery. By assisting the surgeon in correctly identifying parathyroid glands, this device may improve the quality of the operation performed on the patient.
Thyroid
N/A
Solorzano, Carmen
NCT04281875
VICCHN2017

Artificial Tears for the Reduction of Radioiodine Levels in the Nasolacrimal Duct System of Patients with Thyroid Carcinoma following Radioiodine Therapy

Head/Neck

This phase II trial studies how well artificial tears works in reducing radioiodine levels in the nasolacrimal duct system in patients with thyroid carcinoma following radioiodine therapy. Radioactive iodine therapy for thyroid carcinoma has been associated with nasolacrimal duct obstruction. Artificial tears may dilute the amount of radioactive iodine in the tears of the eyes, thus decreasing uptake by the cells lining the nasolacrimal duct system.
Head/Neck
II
Sobel, Rachel
NCT04327999
VICCHN2018

Comparing Two Methods to Follow Patients with Pancreatic Cysts

Pancreatic

The purpose of this study is to compare the two approaches for monitoring pancreatic cysts. The study doctors want to compare more frequent monitoring vs less frequent monitoring in order to learn which monitoring method leads to better outcome for patients with pancreatic cysts.
Pancreatic
N/A
Tan, Marcus
NCT04239573
ECOGGIEA2185

Navigation Endoscopy for the Diagnosis of Indeterminate Lung Nodules, VERITAS Study

Lung

This trial studies how well navigation endoscopy works in diagnosing indeterminate lung nodules. Navigation bronchoscopy is a procedure using technology designed to guide a flexible bronchoscope (a small tube with a camera) through the natural airway route (wind-pipe and bronchi) to access the nodule. Navigation bronchoscopy may be more accurate than the standard computed tomography (CT)-guided biopsy in diagnosing patients with indeterminate lung nodules.
Lung
N/A
Maldonado, Fabien
NCT04250194
VICCTHO19102

18F-FSPG PET / CT in Imaging Patients with Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules

Lung

This phase II trial compares fluorine F 18 L-glutamate derivative BAY94-9392 (18F-FSPG) positron emission tomography (PET) / computed tomography (CT) to the standard of care fludeoxyglucose F-18 (18F-FDG) PET / CT in imaging patients with newly diagnosed lung cancer or indeterminate pulmonary nodules. PET / CT uses a radioactive glutamate (one of the common building blocks of protein) called 18F-FSPG which may be able to recognize differences between tumor and healthy tissue. Since tumor cells are growing, they need to make protein, and other building blocks, for cell growth that are made from glutamate and other molecules. PET / CT using a radioactive glutamate may be a more effective method of diagnosing lung cancer than the standard PET / CT using a radioactive glucose (sugar), such as 18F-FDG.
Lung
II
Massion, Pierre
NCT02448225
VICCTHO1524

Screening Methods for Early Diagnosis of Lung Cancer in Current or Former Smokers

Multiple Cancer Types

This trial studies methods of detecting lung cancer at an earlier stage in current or former smokers with a special type of computed tomography (CT) scan and by testing genes and proteins in biospecimens (blood, urine, sputum, and tissue samples) collected at the time of bronchoscopy (examination of the airway). Analyzing these methods may provide an early detection of lung cancer in current or former smokers when it is more amenable to a cure.
Lung, Miscellaneous, Non Small Cell
N/A
Massion, Pierre
NCT01475500
VICCTHO1078

Registry Study for Talimogene Laherparepvec

Melanoma

A Registry Study to Evaluate the Survival and Long-Term Safety of Subjects Who Previously Received Talimogene Laherparepvec in Amgen or BioVEX-Sponsored Clinical Trials
Melanoma
N/A
Johnson, Douglas
NCT02173171
VICCMEL14103

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