Clinical Trials Search at Vanderbilt-Ingram Cancer Center
Evolutionary Inspired Therapy for the Treatment of Fusion Positive Newly Diagnosed, Metastatic Rhabdomyosarcoma
Multiple Cancer Types
This phase II trial investigates evolutionary inspired therapy in treating fusion positive rhabdomyosarcoma that is newly diagnosed and has spread to other places in the body (metastatic). Chemotherapy drugs, such as vinorelbine, vincristine sulfate, and actinomycin D, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Cyclophosphamide is used to decrease the body's immune response and may inhibit DNA replication and initiate cell death. This study is being done to determine which of 4 different therapeutic treatments will have the best chance of the disease not worsening or coming back.
Pediatrics,
Sarcoma
II
Borinstein, Scott
NCT04388839
VICCPED2134
Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Sarcoma
Sarcoma
This is a study to investigate the efficacy and safety of ADP-A2M4 in HLA-A*02 eligible and
MAGE-A4 positive subjects with metastatic or inoperable (advanced) Synovial Sarcoma (Cohort 1
and Cohort 2) or MRCLS (Cohort 1) .
MAGE-A4 positive subjects with metastatic or inoperable (advanced) Synovial Sarcoma (Cohort 1
and Cohort 2) or MRCLS (Cohort 1) .
Sarcoma
II
Keedy, Vicki
NCT04044768
VICCSAR1948
Neuroblastoma Biology Studies
Multiple Cancer Types
Neuroblastoma (Pediatrics),
Pediatrics
N/A
Benedetti, Daniel
NCT00256763
CCGANBL00B1
Preserving Fertility After Colorectal Cancer: The PREFACE Study
Multiple Cancer Types
Colon,
Rectal
N/A
Holowatyj, Andreana
NCT05239338
VICCGI2186
Novel Gastrointestinal Cancer Markers in Tissue and Biofluids
Gastrointestinal
Gastrointestinal
Gastrointestinal
N/A
Beauchamp, Robert
NCT00899626
VICCGI0283
Prospective, Randomized, Crossover Trial Comparing Recombinant von Willebrand Factor (rVWF) vs. Tranexamic Acid (TA) to Minimize Menorrhagia in Women with von Willebrand Disease: The VWD Minimize Study
Multiple Cancer Types
Gynecologic,
Hematologic
III
Wheeler, Allison
NCT02606045
VICCNCBH1961