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Clinical Trials Search at Vanderbilt-Ingram Cancer Center



Storage and Research Use of Human Biospecimens from Melanoma Patients and Clinical Testing for the Assignment of Therapy

Melanoma

Melanoma
N/A
Johnson, Douglas
NCT01205815
VICCMEL09109

EARLY TAVR

Not Available
N/A
Barker, Colin
NCT03042104
VALV0003

Pilot Study of ctDNA and Imaging Characteristics as Biomarkers of Disease-related Outcomes in Patients with Localized Leiomyosarcoma Receiving Chemotherapy

Sarcoma

Sarcoma
N/A
Davis, Elizabeth
NCT04925089
VICCSAR2121

CSPOT - Conduction System Pacing Optimized Therapy

Not Available
Richardson, Travis
NCT04905290
CRE-ARR0007

CLASP II TR

Not Available
N/A
Barker, Colin
NCT04097145
VALV0004

Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries

Hematologic

Hematologic
N/A
Kassim, Adetola
NCT04920474
NMDPCTT0346

REPAIR MR

Not Available
N/A
Barker, Colin
NCT04198870
VALV0007

ADVANTAGE-AF - A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation

Not Available
Ellis, Christopher
NCT05443594
CRE-ARR0017


Evaluating the Use of Dual Imaging Techniques for Detection of Disease in Patients with Head and Neck Cancer

Phase I

This phase I trial evaluates the safety and effectiveness of using two imaging techniques, indium In 111 panitumumab (111In-panitumumab) with single photon emission computed tomography (SPECT)/computed tomography (CT) and panitumumab-IRDye800 fluorescence imaging during surgery (intraoperative), to detect disease in patients with head and neck cancer. 111In-panitumumab is an imaging agent made of a monoclonal antibody that has been labeled with a radioactive molecule called indium In 111. The agent targets and binds to receptors on tumor cells. This allows the cells to be visualized and assessed with SPECT/CT imaging techniques. SPECT is special type of CT scan in which a small amount of a radioactive drug is injected into a vein and a scanner is used to make detailed images of areas inside the body where the radioactive material is taken up by the cells. CT is an imaging technique for examining structures within the body by scanning them with x-rays and using a computer to construct a series of cross-sectional scans along a single axis. Panitumumab-IRDye800 is an imaging agent composed of panitumumab, a monoclonal antibody, linked to a fluorescent dye called IRDye800. Upon administration, panitumumab-IRDye800 targets and binds to receptors on tumor cells. This allows the tumor cells to be detected using fluorescence imaging during surgery. Adding 111In-panitumumab SPECT/CT imaging to intraoperative panitumumab-IRDye800 fluorescence imaging may be more effective at detecting disease in patients with head and neck cancer.
Phase I
I
Rosenthal, Eben
NCT05945875
VICC-EDHAN23204P

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