Intraoperative Identification and Stimulation of the Glossopharyngeal Nerve
Intraoperative Identification and Stimulation of the Glossopharyngeal Nerve
Published data suggest that the glossopharyngeal nerve innervates pharyngeal musculature important for maintenance of upper airway patency. The investigators propose a study examining the anatomic variation of the glossopharyngeal nerve and the effect of electrical stimulation on muscle recruitment and upper airway patency.
Head/Neck
N/A
Adults
Not Available
Not Available
Ceremsak, John
Local
Vanderbilt University
02-22-2023
Eligibility
18 Years and older
ALL
false
Inclusion Criteria:
Consenting adults with BMI 25 and 40 kg/m2
Consenting adults with BMI 25 and 40 kg/m2
Planned resection of parapharyngeal space (PPS) mass without clinical evidence of cranial nerve function deficits based on physical examination
Planned resection of parapharyngeal space (PPS) mass without clinical evidence of cranial nerve function deficits based on physical examination
History of moderate-to-severe Obstructive Sleep Apnea (OSA) as confirmed by previous polysomnogram OR high risk for OSA based on STOP-BANG criteria (STOP-BANG score 3)
History of moderate-to-severe Obstructive Sleep Apnea (OSA) as confirmed by previous polysomnogram OR high risk for OSA based on STOP-BANG criteria (STOP-BANG score 3)
Exclusion Criteria:
Unable to consent for research due to a pre-existing neurologic condition or language barriers as determined by PI
Unable to consent for research due to a pre-existing neurologic condition or language barriers as determined by PI
History of other primary sleep-related breathing disorder (e.g., central, or complex sleep apnea).
History of other primary sleep-related breathing disorder (e.g., central, or complex sleep apnea).
Previous pharyngeal surgery excluding tonsillectomy (e.g. cleft palate repair, uvulopalatopharyngoplasty)
Previous pharyngeal surgery excluding tonsillectomy (e.g. cleft palate repair, uvulopalatopharyngoplasty)
Prior history of head and/or neck chemoradiation therapy
Prior history of head and/or neck chemoradiation therapy
Existing indwelling neurostimulation device (e.g. pacemaker; spinal, vagal, or hypoglossal nerve stimulator)
Existing indwelling neurostimulation device (e.g. pacemaker; spinal, vagal, or hypoglossal nerve stimulator)
Consenting adults with BMI 25 and 40 kg/m2
Consenting adults with BMI 25 and 40 kg/m2
Planned resection of parapharyngeal space (PPS) mass without clinical evidence of cranial nerve function deficits based on physical examination
Planned resection of parapharyngeal space (PPS) mass without clinical evidence of cranial nerve function deficits based on physical examination
History of moderate-to-severe Obstructive Sleep Apnea (OSA) as confirmed by previous polysomnogram OR high risk for OSA based on STOP-BANG criteria (STOP-BANG score 3)
History of moderate-to-severe Obstructive Sleep Apnea (OSA) as confirmed by previous polysomnogram OR high risk for OSA based on STOP-BANG criteria (STOP-BANG score 3)
Exclusion Criteria:
Unable to consent for research due to a pre-existing neurologic condition or language barriers as determined by PI
Unable to consent for research due to a pre-existing neurologic condition or language barriers as determined by PI
History of other primary sleep-related breathing disorder (e.g., central, or complex sleep apnea).
History of other primary sleep-related breathing disorder (e.g., central, or complex sleep apnea).
Previous pharyngeal surgery excluding tonsillectomy (e.g. cleft palate repair, uvulopalatopharyngoplasty)
Previous pharyngeal surgery excluding tonsillectomy (e.g. cleft palate repair, uvulopalatopharyngoplasty)
Prior history of head and/or neck chemoradiation therapy
Prior history of head and/or neck chemoradiation therapy
Existing indwelling neurostimulation device (e.g. pacemaker; spinal, vagal, or hypoglossal nerve stimulator)
Existing indwelling neurostimulation device (e.g. pacemaker; spinal, vagal, or hypoglossal nerve stimulator)
