Hereditary Cancer Program
Hereditary cancers result from a genetic change, or mutation, that is passed down in a family. People with a change in one of these genes have a hereditary cancer syndrome and a higher chance of getting certain cancers.
The Clinical and Translational Hereditary Cancer Program encompasses research, clinical, and educational efforts to generate and translate new insights in hereditary cancer genetics into clinical care. The program is directed by Georgia Wiesner, M.D., and includes physicians, nurse practitioners, and genetic counselors with expertise in hereditary cancer.
Hereditary Cancer Research
- The Vanderbilt Hereditary Cancer Registry: The overall purpose of this registry is to identify genetic factors that predispose to tumor development and affect outcomes.
- Inherited Cancer Registry (ICARE) Initiative: The purpose of the Inherited CAncer REgistry (ICARE) Initiative is to provide individuals interested in participating in studies focused on inherited cancer predisposition the opportunity to enroll in a research registry. For more information or to enroll, visit the ICARE website. Read the latest ICARE Newsletter. CARE Newsletter
- Colon Cancer Research: It is well established that germline mutations of some of the already known colon cancer susceptibility genes confer a marked risk of early onset colon cancer. We are interested in identifying additional genetic variants that contribute to the risk for developing colon cancer.
- Lung Cancer Research: We are trying to understand whether inherited factors may partly explain the development of lung cancer in patients who did not smoke.