A Practical Approach to Curate Clonal Hematopoiesis of Indeterminate Potential in Human Genetic Datasets.

Vlasschaert, C., Mack, T., Heimlich, J.B., Niroula, A., Uddin, M.M., Weinstock, J.S., Sharber, B., Silver, A.J., Xu, Y., Savona, M.R. (TR), Gibson, C.J., Lanktree, M.B., Rauh, M.J., Ebert, B.L., Natarajan, P., Jaiswal, S. & Bick, A.G. (CE).

Blood 2023; PMID:36652671.

Allogeneic BCMA-targeting CAR T Cells in Relapsed/Refractory Multiple Myeloma: Phase 1 UNIVERSAL Trial Interim Results

Mailankody, S., Matous, J.V., Chhabra, S., Liedtke, M., Sidana, S., Oluwole, O.O. (TR), Malik, S., Nath, R., Anwer, F., Cruz, J.C., Htut, M., Karski, E.E., Lovelace, W., Dillon, M., Butz, E., Ying, W., Balakumaran, A. & Kumar, S.K. 

Nat Med 2023; PMID:36690811.

Rare Immune-related Adverse Events in Patients with Melanoma: Incidence, Spectrum, and Clinical Presentations.

Park, B.C., Narayanan, S., Gavraldis, A., Ye, F., Fan, R., Sullivan, R.J., Boland, G., Reynolds, K.L., Balko, J.M. (BC), Carlino, M.S., Long, G.V., Zubiri, L., Menzies, A.M. & Johnson, D.B. (TR). 

Oncoimmunology 12(1):2188719, 2023; PMC10012911.

PI3K Inhibition Restores and Amplifies Response to Ruxolitinib in Patients with Myelofibrosis.

Moyo, T.K., Kishtagari, A., Villaume, M., McMahon, B., Mohan, S.R., Stopczynski, T., Chen, S.C., Fan, R., Huo, Y., Moon, H., Tang, Y., Bejan, C.A., Childress, M., Anderson, I., Rawling, K., Simons, R.M., Moncrief, A., Caza, R., Dugger, L., Collins, A., Dudley, C.V., Ferrell, P.B. (TR), Byrne, M., Strickland, S.A., Ayers, G.D., Landman, B.A., Mason, E.F., Mesa, R.A., Palmer, J.M., Michaelis, L.C. & Savona, M.R. (TR).

Clin Cancer Res 2023; PMID:37036505.

Longitudinal Lung Cancer Prediction Convolutional Neural Network Model Improves the Classification of Indeterminate Pulmonary Nodules.

Paez, R., Kammer, M.N., Balar, A., Lakhani, D.A., Knight, M., Rowe, D., Xiao, D., Heideman, B.E., Antic, S.L., Chen, H., Chen, S.C., Peikert, T., Sandler, K.L. (CO), Landman, B.A., Deppen, S.A. (CO), Grogan, E.L. (CO) & Maldonado, F. (TR).

Sci Rep 13(1):6157, 2023; PMID:37061539.

Integrative Analysis of a Large Real-world Cohort of Small Cell Lung Cancer Identifies Distinct Genetic Subtypes and Insights into Histological Transformation.

Sivakumar, S., Moore, J.A., Montesion, M., Sharaf, R., Lin, D.I., Colon, C.I., Fleischmann, Z., Ebot, E.M., Newberg, J.Y., Mills, J.M., Hegde, P.S., Pan, Q., Dowlati, A., Frampton, G.M., Sage, J. & Lovly, C.M. (TR).

Cancer Discov 2023; PMID:37062002.

Augmented-Reality Surgery To Guide Head And Neck Cancer Re-Resection: A Feasibility And Accuracy Study

Prasad, K., Miller, A., Sharif, K., Colazo, J.M., Ye, W., Necker, F., Baik, F., Lewis, J.S., Rosenthal, E. (TR), Wu, J.Y. & Topf, M.C. (TR). 

Ann Surg Oncol 2023; PMID:37133570.

A Retrospective Multi-Institutional Cohort Analysis Of Clinical Characteristics And Outcomes In Dedifferentiated Chondrosarcoma

Bui, N., Dietz, H., Farag, S., Hirbe, A.C., Wagner, M.J., Van Tine, B.A., Ganjoo, K., Jones, R.L., Keedy, V.L. (TR) & Davis, E.J. (TR).

Cancers (Basel) 15(9), 2023; PMID:37174084.

Prospective Cardiovascular Surveillance Of Immune Checkpoint Inhibitor-Based Combination Therapy In Patients With Advanced Renal Cell Cancer: Data From The Phase Iii Javelin Renal 101 Trial

Rini, B.I. (TR), Moslehi, J.J., Bonaca, M., Schmidinger, M., Albiges, L., Choueiri, T.K., Motzer, R.J., Atkins, M.B., Haanen, J., Mariani, M., Wang, J., Hariharan, S. & Larkin, J.

J Clin Oncol :JCO2101806, 2022; PMID:35239416.

Axicabtagene Ciloleucel As First-Line Therapy In High-Risk Large B-Cell Lymphoma: The Phase 2 Zuma-12 Trial

Neelapu, S.S., Dickinson, M., Munoz, J., Ulrickson, M.L., Thieblemont, C., Oluwole, O.O. (TR), Herrera, A.F., Ujjani, C.S., Lin, Y., Riedell, P.A., Kekre, N., de Vos, S., Lui, C., Milletti, F., Dong, J., Xu, H. & Chavez, J.C.

Nat Med 2022; PMID:35314842.

Factors For Differential Outcome Across Cancers In Clinical Molecule-Targeted Fluorescence Imaging

Zhou, Q., van den Berg, N.S., Kang, W., Pei, J., Nishio, N., van Keulen, S., Engelen, M.A., Lee, Y.J., Hom, M., Vega Leonel, J.C.M., Hart, Z., Vogel, H., Cayrol, R., Martin, B.A., Roesner, M., Shields, G., Lui, N., Gephart, M.H., Raymundo, R.C., Yi, G., Granucci, M., Grant, G.A., Li, G. & Rosenthal, E.L. (TR).

J Nucl Med 63(11):1693-1700, 2022; PMID:35332092.

 Distinct Patterns Of Clonal Evolution Drive Myelodysplastic Syndrome Progression To Secondary Acute Myeloid Leukemia

Guess, T., Potts, C.R., Bhat, P., Cartailler, J.A., Brooks, A., Holt, C., Yenamandra, A., Wheeler, F.C., Savona, M.R. (TR), Cartailler, J.P. & Ferrell, P.B. (TR).

Blood Cancer Discov 2022; PMID:35522837.

Evaluation Of The Molecular Landscape Of Pediatric Thyroid Nodules And Use Of A Multigene Genomic Classifier In Children

Gallant, J.N., Chen, S.C., Ortega, C.A., Rohde, S.L., Belcher, R.H., Netterville, J.L., Baregamian, N., Wang, H., Liang, J., Ye, F., Nikiforov, Y.E., Nikiforova, M.N. & Weiss, V.L. (TR).

JAMA Oncol 2022; PMID:35679040.

Feasibility Of Outpatient Administration Of Axicabtagene Ciloleucel And Brexucabtagene Autoleucel Using Telemedicine Tools: The Vanderbilt Experience

Dholaria, B. (TR), Mehraban, N., Baer, B., Long, N., Jayani, R.V., Byrne, M.T., Kassim, A.A. (TR), Engelhardt, B.G. (TR), Savani, B.N. & Oluwole, O.O. (TR).

Br J Haematol 2022; PMID:35765247.

Ligand-Independent Integrin Beta1 Signaling Supports Lung Adenocarcinoma Development

Haake, S.M. (TR), Plosa, E.J., Kropski, J.A., Venton, L.A., Reddy, A., Bock, F., Chang, B.T., Luna, A.J., Nabukhotna, K., Xu, Z.Q., Prather, R.A., Lee, S., Tanjore, H., Polosukhin, V.V., Viquez, O.M., Jones, A., Luo, W., Wilson, M.H., Rathmell, W.K. (GM), Massion, P.P., Pozzi, A. (HT), Blackwell, T.S. (TR) & Zent, R. (HT).

JCI Insight 2022; PMID:35763345.

Allele-Specific Activation, Enzyme Kinetics, And Inhibitor Sensitivities Of Egfr Exon 19 Deletion Mutations In Lung Cancer

Brown, B.P., Zhang, Y.K., Kim, S., Finneran, P., Yan, Y., Du, Z., Kim, J., Hartzler, A.L., LeNoue-Newton, M.L., Smith, A.W., Meiler, J. (CB) & Lovly, C.M. (TR).

Proc Natl Acad Sci U S A 119(30):e2206588119, 2022; PMID:35867821.

 89Zr-Panitumumab Combined With 18F-Fdg-Pet Improves Detection And Staging Of Head And Neck Squamous Cell Carcinoma

Lee, Y.J., van den Berg, N.S., Duan, H., Azevedo, E.C., Ferri, V., Hom, M., Raymundo, R.C., Valencia, A., Castillo, J., Shen, B., Zhou, Q., Freeman, L., Koran, M.E., Kaplan, M.J., Colevas, A.D., Baik, F.M., Chin, F.T., Martin, B.A., Iagaru, A. & Rosenthal, E.L. (TR).

Clin Cancer Res 2022; PMID:35929985.

Archetype Tasks Link Intratumoral Heterogeneity To Plasticity And Cancer Hallmarks In Small Cell Lung Cancer

Groves, S.M., Ildefonso, G.V., McAtee, C.O., Ozawa, P.M.M., Ireland, A.S., Stauffer, P.E., Wasdin, P.T., Huang, X., Qiao, Y., Lim, J.S., Bader, J., Liu, Q., Simmons, A.J., Lau, K.S. (CB), Iams, W.T. (TR), Hardin, D.P., Saff, E.B., Holmes, W.R., Tyson, D.R., Lovly, C.M. (TR), Rathmell, J.C. (HT), Marth, G., Sage, J., Oliver, T.G., Weaver, A.M. (HT) & Quaranta, V. (CB). 

Cell Syst 2022; PMID:35981544.

Selective Inhibition Of Mcl1 Overcomes Venetoclax-Resistance In A Murine Model Of Myelodysplastic Syndromes

Fischer, M.A., Song, Y., Arrate, M.P., Gbyli, R., Villaume, M.T., Smith, B.N., Childress, M.A., Stricker, T.P., Halene, S. & Savona, M.R. (TR).

Haematologica 2022; PMID:35979721.

Adjuvant Atezolizumab Versus Placebo For Patients With Renal Cell Carcinoma At Increased Risk Of Recurrence Following Resection (Immotion010): A Multicentre, Randomised, Double-Blind, Phase 3 Trial

Pal, S.K., Uzzo, R., Karam, J.A., Master, V.A., Donskov, F., Suarez, C., Albiges, L., Rini, B. (TR), Tomita, Y., Kann, A.G., Procopio, G., Massari, F., Zibelman, M., Antonyan, I., Huseni, M., Basu, D., Ci, B., Leung, W., Khan, O., Dubey, S. & Bex, A.

Lancet 2022; PMID:36099926.

First-In-Human Phase I/II, Open-Label Study Of The Anti-Ox40 Agonist Incagn01949 In Patients With Advanced Solid Tumors

Davis, E.J. (TR), Martin-Liberal, J., Kristeleit, R., Cho, D.C., Blagden, S.P., Berthold, D., Cardin, D.B. (GI), Vieito, M., Miller, R.E., Hari Dass, P., Orcurto, A., Spencer, K., Janik, J.E., Clark, J., Condamine, T., Pulini, J., Chen, X. & Mehnert, J.M.

J Immunother Cancer 10(10), 2022; PMID:36316061.

Wnt Signaling In The Phenotype And Function Of Tumor-Associated Macrophages

Tigue, M.L., Loberg, M.A., Goettel, J.A., Weiss, W.A., Lee, E. & Weiss, V.L. (TR).

Cancer Res 2022; PMID:36214645.

Shape-Sensing Robotic-Assisted Bronchoscopy Vs Digital Tomosynthesis-Corrected Electromagnetic Navigation Bronchoscopy: A Comparative Cohort Study Of Diagnostic Performance

Low, S.W., Lentz, R.J., Chen, H., Katsis, J., Aboudara, M.C., Whatley, S., Paez, R., Rickman, O.B. & Maldonado, F. (TR).

Chest 2022; PMID:36441041.

T Cells Specific For Α-Myosin Drive Immunotherapy-Related Myocarditis

Axelrod, M.L., Meijers, W.C., Screever, E.M., Qin, J., Carroll, M.G., Sun, X., Tannous, E., Zhang, Y., Sugiura, A., Taylor, B.C., Hanna, A., Zhang, S., Amancherla, K., Tai, W., Wright, J.J., Wei, S.C., Opalenik, S.R., Toren, A.L., Rathmell, J.C. (HT), Ferrell, P.B. (TR), Phillips, E.J., Mallal, S. (ZY), Johnson, D.B. (TR), Allison, J.P., Moslehi, J.J. & Balko, J.M. (BC).

Nature 2022; PMID:36385524.

Axatilimab For Chronic Graft-Versus-Host Disease After Failure Of At Least Two Prior Systemic Therapies: Results Of A Phase I/Ii Study

Kitko, C.L. (TR), Arora, M., DeFilipp, Z., Zaid, M.A., Di Stasi, A., Radojcic, V., Betts, C.B., Coussens, L.M., Meyers, M.L., Qamoos, H., Ordentlich, P., Kumar, V., Quaranto, C., Schmitt, A., Gu, Y., Blazar, B.R., Wang, T.P., Salhotra, A., Pusic, I., Jagasia, M. & Lee, S.J.

J Clin Oncol :JCO2200958, 2022; PMID:36459673.