A Randomized, Double Blind, Phase 3 Study of Chemotherapy with or without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

Disease Sites:

Pancreatic

Staging:

Phase III

Age Group:

Adults

Therapies:

Chemotherapy - cytotoxic, Mol. targeted/Immunotherapy/Biologics

Drugs:

Fluorouracil (5-FU), Folinic Acid, Gemcitabine, INCB161734, Irinotecan, Leucovorin, Nab-Paclitaxel, Oxaliplatin

Principal Investigator(s):

Cardin, Dana

Scope:

International

Participating Institutions:

Vanderbilt University

Open Date:

09-15-2026

Trial Type:

Treatment

Protocol ID:

VICCGI26024

Eligibility

Ages Eligible for Study:

Not Available

Genders Eligible for Study:

Not Available

Accepts Healthy Volunteers?:

Not Available