Dr. Osterman is a practicing medical oncologist, informatician, Clinical Director in the Office of the Chief Health Information Officer at Vanderbilt University Medical Center (VUMC), and Director of Cancer Clinical Informatics in the Vanderbilt-Ingram Cancer Center. He is board certified in internal medicine, medical oncology, and clinical informatics and completed a master of science in biomedical informatics at Vanderbilt University. He has dual faculty appointments at VUMC in the Department of Biomedical Informatics and the Department of Medicine in the Division of Hematology and Oncology.

Dr. Osterman's clinical interest within oncology is lung cancer. He leads the Clinical Cancer Informatics Innovation (C2I2) group whose research focuses on applying clinical informatics methods across the cancer care continuum. Current projects include identifying patients for lung cancer screening, automated clinical trial matching, and using predictive analytics to anticipate toxicity to immunotherapy. As part of this work their team develops tools used for both research and to directly support patient care.

Nationally, Dr. Osterman is involved several national efforts to improve the availability of oncology-specific EHR data to support quality improvement across oncology practices. Dr. Osterman serves on the National Comprehensive Cancer Network (NCCN) Electronic Health Record (EHR) workgroup and Patient Reported Outcomes (PRO) workgroup. The focus of these workgroups includes leveraging the EHR to promote innovation and to standardize best practices across cancer centers. He serves on the American Society of Clinical Oncology (ASCO) CancerLinQ Physician Advisory Board, the Minimum Common Oncology Data Elements (mCODE) workgroup, and the Member and Meeting Publications Editorial Board. Dr. Osterman also represents VUMC as a founding member on the Oncology Clinical Trial Information Commons (OCTIC) project which focuses on standardizing how data describing clinical trials are stored. He also serves on the Epic Adult Oncology Steering Board and chairs Epic's Beacon Community Operations Group.