Clinical Trials Search at Vanderbilt-Ingram Cancer Center
A Phase I Trial Combining Triapine with Radiation Therapy for Recurrent Glioblastoma or Astrocytoma
Neuro-Oncology
Neuro-Oncology
Neuro-Oncology
I
Mohler, Alexander
NCT06860594
VICC-NTNEU24156P
Phase 3 Accelerated BEP Trial: A Randomised Phase 3 Trial of Accelerated versus Standard BEP Chemotherapy for Patients with Intermediate and Poor-Risk Metastatic Germ Cell Tumours
Germ Cell (Pediatrics)
Germ Cell (Pediatrics)
Germ Cell (Pediatrics)
III
Borinstein, Scott
NCT02582697
COGAGCT1532
IMPACT: A Clinical Investigation on Improving Peripheral Neuropathy Induced by Chemotherapy with Advanced Compression Technology - A Safety and Efficacy Study
Miscellaneous
Miscellaneous
Miscellaneous
III
Agarwal, Rajiv
NCT07142304
VICCSUPP25037
An Open-Label, Phase 1 Dose Escalation and Phase 2 Dose Expansion Study to Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of SMP-3124LP in Adults with Advanced Solid Tumors
Multiple Cancer Types
Breast,
Head/Neck,
Lung,
Non Small Cell,
Ovarian,
Phase I,
Uterine
I/II
Eng, Cathy
NCT06526819
VICC-DTPHI23348
A Phase II Trial Evaluating Chemotherapy Followed by Response-Based Reduced Radiation Therapy for Patients with Central Nervous System Germinomas
Not Available
II
Esbenshade, Adam
NCT06368817
COGACNS2321
Optimice-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve PCR After Neoadjuvant Chemotherapy with Checkpoint Inhibitor Therapy
Breast
Breast
Breast
III
Abramson, Vandana
NCT05812807
VICC-NTBRE23357
Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs
Pancreatic
Pancreatic
Pancreatic
N/A
Tan, Marcus
NCT04239573
ECOGGIEA2185
A Phase II Randomized Trial of Adjuvant Therapy with Pembrolizumab after Resection of Recurrent/Second Primary Head and Neck Squamous Cell Carcinoma with High Risk Features
Head/Neck
Head/Neck
Head/Neck
II
Choe, Jennifer
NCT04671667
ECOGHNEA3191
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
Multiple Cancer Types
This is a clinical study that has three parts. It is testing a potential new medicine called Sofetabart Mipitecan (Sofe-M) for people with certain types of ovarian, peritoneal, and fallopian tube cancers. Part A enrolls participants with platinum-resistant cancer, meaning their disease progressed during or within six months of platinum-based chemotherapy. Parts B and C enroll participants with platinum-sensitive cancer, whose disease responded and remained controlled for at least six months after completing platinum treatment. The researchers want to find out if Sofe-M works better than the standard treatments that doctors use now and to better understand how safe it is. Each participant's time in the study will depend on how they respond to the treatment.
Gynecologic,
Ovarian
III
Brown, Alaina
NCT07213804
VICCGYN26015
Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System
Lung
Lung
Malignant pleural effusion remains a debilitating complication of end stage cancer, which can be greatly improved by the introduction of the indwelling tunneled pleural catheter (IPC). However, there is no standard of care regarding drainage and limited data on the utility of different drainage techniques. In addition, many patients develop discomfort and chest pain during drainage. The investigators propose to evaluate gravity drainage and suction drainage on quality of life measures and outcomes.
Lung
N/A
Maldonado, Fabien
NCT03831386
VICCTHO19118
