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Alan Tan, M.D.

  • Associate Professor of Genitourinary Oncology

Alan Tan, M.D.

  • Associate Professor of Genitourinary Oncology

alan.tan@vumc.org

Research Program

Research Description

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Matthew Fleming, M.D., Ph.D.

  • Instructor of Cardiology

Matthew Fleming, M.D., Ph.D.

  • Instructor of Cardiology

matthew.r.fleming@vumc.org

Research Program

Research Description

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Sharon Jones, R.N., M.S.

  • Assistant Professor of Nursing

Sharon Jones, R.N., M.S.

  • Assistant Professor of Nursing

sharon.jones@Vanderbilt.Edu

Research Program

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Rahul Bhowmick, Ph.D.

  • Assistant Professor of Biochemistry

Rahul Bhowmick, Ph.D.

  • Assistant Professor of Biochemistry

rahul.bhowmick@Vanderbilt.Edu

Research Program

Research Description

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Katrin Karbstein, Ph.D.

  • Co-Leader, Cancer Cell Biology Research Program
  • Ingram Professor of Cancer Research
  • Professor of Biochemistry

Katrin Karbstein, Ph.D.

  • Co-Leader, Cancer Cell Biology Research Program
  • Ingram Professor of Cancer Research
  • Professor of Biochemistry

katrin.karbstein@vanderbilt.edu

Research Program

Research Description

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Xiaoyu Jiang, Ph.D.

  • Research Assistant Professor of Radiology and Radiological Sciences

Xiaoyu Jiang, Ph.D.

  • Research Assistant Professor of Radiology and Radiological Sciences

xiaoyu.jiang@vumc.org

Research Program

Research Description

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Daniel Benedetti, MD, MA

  • Associate Professor of Pediatrics (Hematology/Oncology)

Daniel Benedetti, MD, MA

  • Associate Professor of Pediatrics (Hematology/Oncology)

daniel.benedetti@vumc.org

Research Program

Research Description

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John Scheel, M.D., Ph.D.. M.P.H

  • Professor of Radiology and Radiological Sciences

John Scheel, M.D., Ph.D.. M.P.H

  • Professor of Radiology and Radiological Sciences

john.scheel@vumc.org

Research Program

Research Description

Have any questions? Contact Us 1-877-936-8422 for more information
The main purpose of the study is to evaluate the safety and tolerability of the combination of elranatamab and carfilzomib and dexamethasone or elranatamab and maplirpacept. There are 2 parts to this study. Part 1 will evaluate the safety and tolerability of elranatamab when given in combination with carfilzomib plus dexamethasone. Part 2 has 2 arms. The first will evaluate the safety and tolerability of elranatamab when given in combination with maplirpacept. The second will identify the optimal dose(s) of elranatamab plus maplirpacept. All study medicines are given over 4-week cycles. Everyone taking part in this study will receive elranatamab as a shot under the skin. Participants in Part 1 will also receive weekly carfilzomib as an IV infusion (given directly into a vein) and dexamethasone either by mouth (as a pill) or by IV infusion. Participants in Part 2 will receive elranatamab in combination with maplirpacept as an IV infusion (given directly into a vein) The investigators will examine the experiences of people receiving the study medicines. This will help determine if the study medicines are safe and can be used for multiple myeloma treatment. Participants will take part in this study for about 2 years after the first dose.
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