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KaCrole Higgins was diagnosed with breast cancer in 2020. “In May 2020, I found a lump in my breast. I cried. By June, it was diagnosed as breast cancer, triple positive, stage 1A. While getting this cancer diagnosis was devastating, it also became an opportunity. Suddenly, the cancer gave me clarity. It gave me clarity about what was important, what was good in my life, what was toxic in my life, and what I needed to do.” Click below to read more of KaCrole’s story |
If Landon Ryan had been diagnosed with bilateral retinoblastoma 10, 20 or 30 years ago, she might not be here today with nearly perfect vision.Thanks to recent improvements in the treatment for this rare form of cancer that almost exclusively affects children under the age of 5, the diagnosis had the power to change Landon’s life when she was 11 months old, but not to take it — or her eyesight. Click below to learn more about Landon and her story. https://momentum.vicc.org/2022/04/brighter-outlook/ |
Expanded Access Program (EAP) for Obecabtagene Autoleucel (Obe-Cel) Out-of-Specification (OOS) in Adult Patients with Acute Lymphoblastic Leukemia
Leukemia
Leukemia
Leukemia
N/A
Oluwole, Olalekan
VICC-CTT25006
An Open-label, Phase 1 Dose Escalation and Phase 2 Dose Expansion Study to Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of SMP-3124LP in Adults with Advanced Solid Tumors
Multiple Cancer Types
Breast,
Head/Neck,
Lung,
Non Small Cell,
Ovarian,
Phase I,
Uterine
I/II
Eng, Cathy
NCT06526819
VICC-DTPHI23348
MCC21704: A Multi-Institution Study of TGFB, Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination with Gemcitabine and Docetaxel in Patients with Relapsed or Refractory Pediatric Bone and Soft Tissue
Multiple Cancer Types
Pediatrics,
Sarcoma
I/II
Borinstein, Scott
NCT05634369
VICCPED24617
A Phase 2, Multicenter, Multi Arm, Study to Evaluate Pembrolizumab (MK- 3475) or MK-1308A (Co-formulated quavonlimab (MK-1308)/pembrolizumab) in Participants with Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer: (MK-1308A-008)
Not Available
II
Not Available
NCT04895722
VICCGI2145
Randomized Phase II Trial of Anti-LAG-3 and Anti-PD-1 Blockade vs SOC in Patients with Recurrent Glioblastoma
Neuro-Oncology
Neuro-Oncology
Neuro-Oncology
II
Mohler, Alexander
NCT06325683
ALLNEUA072201
A First-In-Human, Phase 1, Dose-Escalation Study of SGR-3515 In Participants with Advanced Solid Tumors
Not Available
I
Gibson, Mike
NCT06463340
VICC-DTPHI24100
A Global Study of Volrustomig (MEDI5752) for Participants With Unresected Locally Advanced Head and Neck Squamous Cell Carcinoma Following Definitive Concurrent Chemoradiotherapy
The main purpose of this study is to assess the efficacy and safety of volrustomig compared to observation in participants with unresected locally advanced head and neck squamous cell carcinoma (LA-HNSCC) who have not progressed after receiving definitive concurrent chemoradiotherapy (cCRT).
Not Available
III
Choe, Jennifer
NCT06129864
VICC-DTHAN24071
A Phase I/II Study of M3814 and Avelumab in Combination with Hypofractioned Radiation in Patients with Advanced Metastatic Solid Tumors and Hepatobiliary Malignancies
Not Available
I/II
Heumann, Thatcher
NCT04068194
VICC-NTGIT24020
Phase II Trial to Evaluate Immune-Related Biomarkers for Pathological Response in Stage I-III HER2-Positive Breast Cancer Receiving Neoadjuvant Chemotherapy with Subsequent Randomization to Multi-Epitope HER2 Vaccine vs. Placebo in Patients with Residual Disease Post-Neoadjuvant Chemotherapy
Not Available
II
Not Available
NCT04197687
VICCBRE2241
A Phase 2 Randomized, Open-Label Study Evaluating the Efficacy and Safety of ALLO-501A in Participants with Minimal Residual Disease After Response to First Line Immunochemotherapy for Large B-Cell Lymphoma (ALPHA3)
Not Available
II
Jallouk, Andrew
NCT04416984
VICC-DTCTT24008
