Thoracic
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Radiation Oncology
Thoracic
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NSCLC
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Localized Disease-Unresectable Stage I-IIA
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Localized Disease-Unresectable Stage III
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STAGE IV 1st Line
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VICCTHOP2185
SiCARIO for Tx of Oligometastatic NSCLC Using Biologically-Adaptive Radio Tx
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Key Eligibility:
1. ECOG 0-2
2. No prior systemic therapy for advanced/metastatic NSCLC (prior adjuvant chemotherapy following
complete resection of early-stage NSCLC I-II is allowed)
3. Participants with 5 or fewer brain metastases are eligible if intracranial sites can be treated with
surgery and/or stereotactic radiosurgery, prior to initiation of chemo-immunotherapy
4. Visits: SOC Chemoimmunotherapy plus radiation to oligometastatic sites (frequency of radiation
visits determined on case by case basis)
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Relapsed
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SCLC
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